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It has been shown that GPX1 can alter the activation of NF-B ( In summary, we investigated the role of GPX1 in protecting SGNs against oxidative stress by upregulating or inhibiting the expression of GPX1 in SGNs via the GPX1 mimic ebselen or the gpx1 knockout mouse model, and further determined the mechanistic details behind the neuroprotective effect of GPX1 in SGNs against peroxynitrite injury
Therefore, the sensitivity of these genetic backgrounds, combined with the ease by which Glp and tumorous phenotypes can be observed in living animals, has resulted in the identification of many factors involved in regulating the proliferation vs
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eNeuro (2018) 5(4):118